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Purpose |
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The purpose of this website
is to increase the availability of scientific knowledge related to
the
distribution in human brain of receptor populations thought to be involved
in psychiatric and neurologic disorders, that are the target of efforts
to develop radioligands for use in studies employing positron emission
tomography and SPECT. We are in possession of a large and unique data
base of postmortem human brain autoradiographic receptor studies that
map in high resolution the level of binding in slide mounted section
suitable
for comparison with lower resolution images generated by in vivo scans
using PET or SPECT. Investigators can use their own PET or SPECT scans
to compare to our postmortem images and to our PET studies to determine
the comparability of distribution as an anatomical validation of new
ligands.
This website is a product of the New York State Psychiatric Institute
Neuroscience Department and supported by a grant from The Diane Goldberg
Foundation. |
View
side by side presentation of Autoradiogram, PET and MRI images. 
View
catalogue of six types of autoradiogram images.
View coregistered WAY or McNeil PET scans overlayed upon MRI structural images.